K. Khachanov leads the head-to-head 2-1 since 2018 against B. Van De Zandschulp, over 3 matches.
| Surface | K. Khachanov | B. Van De Zandschulp |
|---|---|---|
| Clay | 1 | 0 |
| Hard | 1 | 1 |
| Date | Winner | Score | Event |
|---|---|---|---|
| May 10, 2026 | K. Khachanov | 2 - 1 | Rome · 1/16-finals · clay |
| Feb. 28, 2023 | B. Van De Zandschulp | 2 - 0 | ATP Dubai · 1/16-finals · hard |
| Feb. 5, 2021 | K. Khachanov | 2 - 1 | Melbourne (Great Ocean Road Open) · Quarter-finals · hard |