J. Sinner leads the head-to-head 7-2 since 2018 against A. Rublev, over 9 matches.
| Date | Winner | Score | Event |
|---|
| May 14, 2026 | J. Sinner | 2 - 0 | Rome · Quarter-finals · clay |
| June 2, 2025 | J. Sinner | 3 - 0 | French Open · 1/8-finals · clay |
| Aug. 17, 2024 | J. Sinner | 2 - 1 | ATP Cincinnati · Quarter-finals · hard |
| Aug. 11, 2024 | A. Rublev | 2 - 1 | Montreal · Quarter-finals · hard |
| Jan. 23, 2024 | J. Sinner | 3 - 0 | ATP Australian Open · Quarter-finals · hard |
| Oct. 28, 2023 | J. Sinner | 2 - 0 | ATP Vienna · Semi-finals · hard |
| March 28, 2023 | J. Sinner | 2 - 0 | ATP Miami · 1/8-finals · hard |
| May 30, 2022 | A. Rublev | 1 - 1 | French Open · 1/8-finals · clay |
| April 14, 2022 | J. Sinner | 2 - 1 | Monte Carlo · 1/8-finals · clay |