F. Cerundolo and L. Musetti are level 2-2 in their head-to-head since 2018 over 4 matches.
| Surface | F. Cerundolo | L. Musetti |
|---|---|---|
| Clay | 1 | 2 |
| Other | 1 | 0 |
| Date | Winner | Score | Event |
|---|---|---|---|
| May 10, 2026 | L. Musetti | 2 - 0 | Rome · 1/16-finals · clay |
| Nov. 21, 2024 | F. Cerundolo | 2 - 0 | ATP Davis Cup - World Group |
| July 27, 2024 | F. Cerundolo | 2 - 1 | ATP Umag · Final · clay |
| July 23, 2022 | L. Musetti | 2 - 0 | Hamburg · Semi-finals · clay |